3ones

The Simplest Stable Structure
March 8, 2010
 
Xconomy San Diego
Tocagen, Developing Anti-Cancer Therapies, Close to Closing on $8M Round
cancer, Gene Therapy, Drug Development Bruce V. Bigelow wrote: San Diegos Tocagen, a biotech developing gene therapy treatments for terminal cancers, says it has raised nearly $7.8 million from 75 investors in a Series D round that began F...
Bruce V. Bigelow wrote:

Memjet, the San Diego printer technology startup that named former Qualcomm COO Len Lauer as its CEO in January, took a step toward becoming a conventional company by naming Mark W. Legg as chief financial officer, according to a statement issued today. Legg was previously the CFO at privately held General Atomics of San Diego. Lauer is in the process of reorganizing Memjet, which was founded by Australian Kia Silverbrook and did not previo...


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Bruce V. Bigelow wrote:

San Diegos Fallbrook Technologies, which is developing a new and more-efficient design for a continuously variable transmission, says today it has signed an agreement with Hodyon of Austin, TX, for joint development of a new air conditioner compressor for medium and heavy-duty vehicles. Financial terms of the agreement were not disclosed. Fallbrook says its deal with Hodyon is part of its broader effort to develop its technology for ...


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Xconomy San Diego


Luke Timmerman wrote:

Isis Pharmaceuticals (NASDAQ: ISIS), the Carlsbad, CA-based biotech company, said today it has earned a $6 million payment from Bristol-Myers Squibb for getting clearance from regulators to begin clinical trials of a new cholesterol-lowering drug. Isis and Bristol are collaborating on BMS-PCSK9Rx, as a targeted antisense therapy which seeks to lower cholesterol by hitting the target PCSK9.

Luke Timmerman wrote:

Roche and Cambridge, MA-based Biogen Idec are halting development of an experimental drug for rheumatoid arthritis because of safety concerns, according a report today by Bloomberg News. The drug, ocrelizumab, was designed to hit the same protein target on cells as the hit antibody ritxumimab, (Rituxan), albeit in a form thought to be more conducive for chronic autoimmune diseases than rituximab, which was originally developed as a cancer drug. Still, ...


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Bruce V. Bigelow wrote:

Qualcomms chairman and CEO says the San Diego wireless company is in the drivers seat when it comes to setting the agenda for the wireless industry. Were here to tell you what that means, so you dont miss the on-ramp.

When Paul Jacobs was named to head San Diegos Qualcomm five years ago, the No. 3 son of Qualcomm founder Irwin Jacobs came across as a bit wonky. But Paul Jacobs is getting better at public speaking, as he demonstrated last week in a ...


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Scientists from Sapphire Energy, UCSD, Scripps, and Protelica Show Genetically Modified Algae Can Make Important Drugs
Life Sciences, innovation, Drug Development Bruce V. Bigelow wrote: Scientists in San Diego and Hayward, CA, have demonstrated the feasibility of using algae to produce commercial levels of human therapeutic proteins that are currently bei...
Luke Timmerman wrote:

HIV has taught the pharmaceutical industry that the best way to fight an infectious virus that resists a single drug is to make a cocktail that attacks the virus in more than one way. Vertex Pharmaceuticals and its competitors are now following a similar formula with new therapies for hepatitis C.

Vertex, the Cambridge, MA-based company with operations in San Diego, offered a glimpse last week into its strategy for a two-drug combo that could signifi...


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March 4, 2010
 
Xconomy San Diego
Bruce V. Bigelow wrote:

The La Jolla Research & Innovation Summit held yesterday at the Salk Institute was a smaller and a much more modest affair than the inaugural summit that Connect CEO Duane Roth organized last year. I have some impressions from the morning presentations:

Climatologist Dan Cayan of UCSDs Scripps Institution of Oceanography explained why multiple computerized models of climate change indicate that Southern California will become significantly hotter ...


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Bruce V. Bigelow wrote:

There was a flurry of San Diego life sciences news over the past week, but weve got it all sorted for you here.

Politicians sometimes complain about voter apathy, but consider the plight of San Diegos La Jolla Pharmaceutical. The biotech, which failed to develop a drug for lupus, has been unable to muster enough shareholder votes to put itself out of businessor to approve a proposed merger with Adamis Pharmaceuticals (OTCBB: ADMP). In ...


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ActivX Biosciences, Showing Life After Takeover, Keeps Innovative Ties in San Diego
Biotech, acquisitions, people Luke Timmerman wrote: Cover business long enough, and some storylines becomes routine. Startup creates something valuable, gets acquired. Valuable thing gets plucked away by big company, cost cuts ensue, jobs ...

 
March 3, 2010
 
GigaOM
OscarRedCarpetfull
The big daddy awards show, The Oscars, is getting with the social-media picture this year and live-streaming from its red carpet to the web. A live show on Oscar.com from 3-5 p.m. PT on Sunday will be followed by behind-the-scenes clips and interv...
t-mobile-3g-data-use
I dont often look at my cellular phone bills, but I happened to glance at the latest one from T-Mobile. My first full monthly billing cycle didnt show anything out of the ordinary, but the monthly data usage happened to catch my eye. I thought I c...

 
 
ReadWriteWeb
Google Index to Go Real Time
Google is developing a system that will enable web publishers of any size to automatically submit new content to Google for indexing within seconds of that content being published. Search industry analyst Danny Sullivan told us today that this co...
Is XBRL The Key To Escaping Small Cap Hell?
Small cap hell is where you end up in about six months after your IPO, when all the high fives and champagne have receded into a distant memory. Unless your company is big enough. How big is big enough? According to Investopedia, small cap refers ...
Never Mind the Valley: Here's SXSW 2010
A ReadWriteWeb Guide For all of our startup friends from coast to coast and around the world, we look forward to seeing you at SXSW Interactive! More and more, we're seeing good folks creating great products outside the SF Bay Area, and we love ...

In the kids book "George Saves the World by Lunchtime", George saves the world through recycling. His four tips are reduce, repair, reuse and recycle. When Toyota decided to build Toyota Conversations Powered by Tweetmeme, they applied the same approach. The collaboration is about more than simply utilizing a social media tool to reach out to customers. It also allows Toyota to meet business objectives like reducing resources, while at the same supporting customer-friendly initiatives such as transparenc...


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March 2, 2010
 
GigaOM
Yahoo TimeSense
Perhaps inspired by the speed of the medium, the integration of real-time tweets and other updates into major search engines has happened more quickly than I might have expected. Its pretty amazing that raw Twitter posts already show up by default...
nov
Elliott Associates, L.P., a hedge fund with a significant position in shares of Novell, after the close of trading in U.S. stock markets today placed an unsolicited offer to buy the open source-focused software company for close to $2 billion. The...
nbcolympics
During the past two weeks, the only time I would remember that the Winter Olympics were underway was when I was looking at the stats of our NewTeeVee blog or checking out Mathew Ingrams Twitter stream. In the case of NewTeeVee, we saw a whole lot ...

 
February 25, 2010
 
ReadWriteWeb
SnapGroups: New Startup Coming From Creator of Yahoo! Groups & Bloglines
Mark Fletcher, the man who built one of the first easy email group services online and sold it to Yahoo! for $400 million, then built former market-leading RSS reader Bloglines and sold it to Ask.com, plans to launch a new service next week called...
Never Mind the Valley: Here's Chicago
Holding down the proverbial fort for the mid-west, Chicago, the Windy City, is the third largest city in the U.S. and the most populous city that doesn't sit on an ocean coast. The city, which does, however, rest on the shore of Lake Michigan, is ...
The 3 Surprising Investment Sources Behind Your VC
While so much of the startup scene is funded by investment capital, it's tough to know exactly where all of that money comes from. In chasing the power behind the investment throne it's easy to believe that everything conspires by the hand of the ...
Buzrr Wants to Be Tweetmeme for Google Buzz
Swedish marketing technologist Dennis Hettema has created a hot-item tracking website for the most-shared items on Google Buzz, called Buzrr. The site is very simple right now, it doesn't include categories, there's no description of how it works...
E-Cards Are Dead... Except on Mother's Day
After looking over recent stats from Hitwise Intelligence on the decline of e-cards and the simultaneous rise of social media, we were stopped mid-yawn by this weird little blip on the radar: On Mothers' Day, e-cards show a less drastic YoY decli...
This Game Is Fixed! Democratized Content v. Voting Rings
TheSixtyOne Seeks to Solve the Problem In an interesting move against those who would manipulate traffic on the social web, music site TheSixtyOne is looking for a programmer who can crack the codes of voting rings. On sites such as Digg, Reddit...
Keeping Out the Trolls: Relevancy in User-Generated Content
In the summer of 2008, J.R. Johnson sold Virtual Tourist to Expedia for $85 million dollars. While Johnson seems like the type of laid back LA entrepreneur that would take some vacation time, his quest for relevancy had him launching a new communi...

 
February 23, 2010
 
ReadWriteWeb
Microsoft to Government CIOs: Choice is Here
At the 8th annual U.S. Public Sector CIO summit in Redmond, Microsoft shared its progress in offering cloud software services to the attendees. The company has been making progress along multiple fronts, showing the power of focus and persistence...
Our Hottest New iPhone App Discoveries: February Edition
Apps on the iPhone, there are so very many of them - how's a person to find the best ones? We look at a whole lot of them here at ReadWriteWeb and we'd like to share with you some of our favorites we've discovered in the month of February. Some ...
ReadWriteWeb Co-Hosting SXSW Party With PBS, NPR & Others
SXSW Interactive is just around the corner, so it's time to make your party plans for Austin, Texas! ReadWriteWeb's SXSW party - in partnership with PBS, NPR, and others - is happening on Sunday, March 14, from 9pm at KLRU's legendary Austin City ...
Startups: Don't Don't Be Be Redundant Redundant On On Buzz Buzz
Tuesday night, ReadWriteWeb announced that we would be taking a new approach to how we use social media to communicate with our readers. Instead of blasting out automated content on Google Buzz as we do with our Twitter and Facebook accounts, we w...
Startup Visa Introduced: Is it a No-Brainer?
Foreign startups with their sights on targeting a U.S. market will be happy to note that as of this morning, Senator John Kerry and Senator Richard Lugar introduced the Startup Visa Act in Washington. In late December we covered the details of the...

We already knew that Facebook had usurped Yahoo's spot as the web's second-most visited website in the U.S. in January, but today, web analytics firm Compete also released its data for the rest of the top 50 sites in in the U.S. Unsurprisingly, most shopping sites registered a large drop in unique visitors since December, while tax services are seeing some of the highest month-to-month growth rates.

Sponsor

Shopping Sites Down

Shopping sites like Walmart.com, Target.com and BestBuy both saw substantial mo...


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DIY Democracy: Civic Participation for the iPhone
Have you ever heard someone proclaim that if you don't vote, then you shouldn't complain? Well, whether or not you vote, we have the perfect iPhone app to make your complaints heard by whatever government official, agency or otherwise - DIY Democr...
Rackspace Cloud: An App Store that Pays
Do you like getting paid? Today, RackSpace Cloud announced a new cloud partner program designed to bring new business to reward partners for bringing hosting to the cloud offerings with the company. Now with the Rackspace program program, rese...
Google App Engine is Down - Backup Data Center Having Problems
Google App Engine is down and there are problems with a backup data center. The problem is affecting untold number of customers. A post at 8:36 a.m. PST to the Google App Engine Group stated: "Since 7:53am PST, App Engine has been experiencing ...
Intel-Lead Initiative Pledges $3.5 Billion To Tech Startups
While the government in Washington slowly inches their way toward a bill to create jobs for Americans, tech corporations and venture capital firms across the nation are teaming up in a private sector effort to create more companies and more jobs i...
Recognizr: Facial Recognition Coming to Android Phones
Swedish software and design company The Astonishing Tribe, also known as TAT, has been developing a rather astonishing augmented reality application for mobile phones. Originally built as a software concept, the Android app called "Recongnizr" is ...
Despite the Rumors, RickRolling Isn't Dead
Dramatic headlines cried out overnight that RickRolling was dead. The original Rick Astley video with more than 30 million views has been pulled from YouTube due to copyright violation. In fact, however, YouTube appears to have simply moved the ...
Italy Attacks Web Democracy with Google Convictions
Italy today attacked the very basis of the read/write Web we focus on here at ReadWriteWeb when it convicted three of four Google employees on trial for failing to comply with the Italian privacy code. In essence, Italy just said that website owne...
2 Ways to Sync Google Buzz with Twitter
Have you ever wanted to sync your Google Buzz "status updates" from Google's new social networking service over to the popular microblogging network Twitter? At launch time, that isn't possible using Buzz's interface. It doesn't allow you to sync ...
Never Mind the Valley: Here's Washington DC
The words "fat cats in Washington" have been uttered in every corner of the nation from Texas to the Bay, yet DC's tech scene is anything but sluggish. Companies like AOL, Nextel, MCI and Uunet found early success in the region and since then, a s...
Wordpress.com Founder Matt Mullenweg: The Cloud is Marketing Speak
The Wordpress.com network went down last week. In the wake of the outage, we started looking at what infrastructure Wordpress.com uses for serving its 10 million blogs. Wordpress.com is run from data centers in Chicago and San Antonio. Layered T...
Despite Tough Talk, Google Still Censoring in China
On January 12 Google claimed that hackers from China had attempted to break into its infrastructure, in order to access the Gmail accounts of Chinese human rights activists. The "attackers" had tried to access email content, but they onl...
Open Thread: Old Fogeys v. Young Whippersnappers, Ageism in Tech
In the past, we've talked a bit about issues of gender and technology, but today, this blog post brought another important aspect of tech and discrimination to our attention. We polled some of our friends on Google Buzz and asked whether ageism i...

Hey, RWW friends and fans! As some of you may have noticed, we've been tinkering around with our new team Buzz account today. We've decided to do something a little bit different with this network, and we really hope you'll like it.

We know a lot of you follow us on Twitter of are our Facebook fans, and sometimes the constant streams of blog posts and observations can be as impersonal as they are informative or interesting. And occasionally, you might also catch a duplicate update.

We've decided that the...


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These days, the web of connections between various social media sites, search engine giants, old software stand-bys and hot Internet start-ups is starting to look like the diagram of an incestuous group of teenagers. And today, that web got one more strand, as Yahoo and Twitter announced a partnership that will bring the two companies closer together.

The deal comes on the heels of this morning's revelation that Twitter will be soon unveiling an advertising platform, which means more tweets seen in more pl...


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Gowalla is the Anti-FarmVille
Millions of people click click click their way mindlessly through repetitive casual games like FarmVille every day. Such games spread like a virus, infecting Facebook news feeds and eating up big chunks of the precious little time on earth that p...
How the Real-Time Web Will Impact Social Change
Earlier this month Amy Sample Ward interviewed ReadWriteWeb's Marshall Kirkpatrick about our report on the real-time Web and how real time impacts the world of nonprofit organizations. Sample Ward helps nonprofits, community groups and those in th...

 
February 22, 2010
 
GigaOM
hooked-small
Hooked Media, a venture-backed startup based in San Francisco, launched a platform today that it hopes will take social and casual games like Farmville and Bejeweled and give them a life beyond Facebook or a single web site, allowing players to ...
internet rural
The Federal Communications Commission this morning released results from its national broadband consumer survey, and the findings will surprise no one. The FCC, which will officially present the document in Washington on Tuesday morning, found tha...

Forget everything you did today. Clear your schedule and spend the next half hour watching this video. It is a presentation by Jesse Schell, founder of Schell Games and former creative director of the Disney Imagineering Virtual Reality Studio. A veteran game designer, he is also on the faculty of the Entertainment Technology Center at Carnegie Mellon University.

In a recent talk at the DICE 2010 conference held last week in Las Vegas, he gave a presentation called Design Outside The Box. It is the most mi...


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NielsenSNSDec
Twitter disclosed earlier today that it has crossed 50 million tweets per day. Thats a stat with a direct equivalent: Facebook status updates. As of earlier this month, Facebook had 60 million status updates per day. To be fair, Facebook doesnt se...

 
February 18, 2010
 
Xconomy San Diego
Denise Gellene wrote:

Some local biotechnology companies landed funding deals during the past week. Weve got that and other highlights below.

Tioga Pharmaceuticals raised $18 million in private equity to fund a late-stage clinical trial of asimadoline, its experimental drug for irritable bowel disorder.

San Diego received $4.95 million of $225 million in stimulus funding awarded nationwide to increase educational, training, and placement services for people se...


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Luke Timmerman wrote:

Just before the financial crisis hit in September 2008, Cambridge, MA-based Proteostasis Therapeutics was fortunate to snag $45 million of initial venture financing to pursue a dream. It has been pretty quiet since then. But behind the scenes, the idea has morphed into a company built to make convenient oral pills for diseases of aging.

Proteostasis was started by a big-name investor syndicate led by HealthCare Ventures. The founding science came from the ...


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Renewable Energy Investor Says Wind Industry Ripe for Innovation
renewable energy, Financing, wind power Bruce V. Bigelow wrote: You could say I blew into the wind power event that Cleantech San Diego organized here last week. The canapés were gone by the time I arrived, but the show was just getting st...
Bruce V. Bigelow wrote:

San Diego drug developer Hollis-Eden Pharmaceuticals says it has changed its name to Harbor BioSciences, nearly a year after the company fired Richard Hollis, the biotechs namesake founder and CEO, for cause unknown. Harbor BioSciences also changed its ticker symbol to (NASDAQ: HRBR), saying that shares would begin trading under the new ticker today. The biotech says it is continuing to develop a new steroid analog that stimula...


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